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ScienceDaily · 08/20/2024 22:18 EDT

Researchers teaching artificial intelligence about frustration in protein folding

Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the... Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 22:18 EDT

Researchers use AI tools to uncover connections between radiotherapy for lung cancer and heart complications

Researchers have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

Fossil hotspots in Africa obscure a more complete picture of human evolution

A new study shows how the mismatch between where fossils are preserved and where humans likely lived may influence our understanding of early human evolution. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

'Molecular compass' points way to reduction of animal testing

Machine learning models have become increasingly popular for risk assessment of chemical compounds. However, they are often considered 'black boxes' due to their lack of transparency. To increase confidence in these models, researchers proposed carefully identifying the areas of chemical space where these models are weak. They developed an innovative software tool for this purpose, and the results of this research approach have just been published. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

Explanation found for X-ray radiation from black holes

Researchers have succeeded in something that has been pursued since the 1970s: explaining the X-ray radiation from the black hole surroundings. The radiation originates from the combined effect of the chaotic movements of magnetic fields and turbulent plasma gas. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

Deadly sea snail toxin could be key to making better medicines

Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

New worm study paves way for better RNA-based drugs to treat human disease

Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

Aceneuramic acid is the first approved drug for GNE myopathy treatment

A clinical trial has led to the approval of a treatment for patients with a rare, muscle-weakening disease called GNE myopathy. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:45 EDT

How early-life antibiotics turn immunity into allergy

Researchers have shown how and why the depletion of microbes in a newborn's gut by antibiotics can lead to lifelong respiratory allergies. The research team identified a specific cascade of events that lead to allergies and asthma, opening many new avenues for exploring potential preventions and treatments. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Type 2 diabetes increased by almost 20% over a decade in U.S., study finds

Type 2 diabetes increased by almost 20% between 2012 and 2022 in the United States, according to a new study. The researchers found an increase in diabetes among all sociodemographic groups. But non-Hispanic Black people were particularly hard hit by the disease, with just under 16% of Black study participants reporting being diagnosed with Type 2 diabetes. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Precision therapy for metastatic prostate cancer improves survival

Men with metastatic castration-resistant prostate cancer should be treated primarily with second-generation hormone drugs, which offer better treatment response and longer life expectancy than chemotherapy. However, the effect depends on which mutations the patient's tumor carries, according to a new study. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Growth from adversity: How older adults bounced back from the COVID-19 pandemic

The study highlights the remarkable resilience of older adults (median age 86) during the COVID-19 pandemic. Disruptions to their routines led many to discover new hobbies like gardening and painting and explore virtual activities such as online yoga. While 51% experienced psychosocial issues such as anxiety and depression, 86% did not see worsening of their medical conditions and supported pandemic precautions. Despite the hardships, including the loss of residents and... Read more ›

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ScienceDaily
ScienceDaily 1 place · 08/20/2024 12:44 EDT

Scientists discover new code governing gene activity

A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Scientists harness quantum microprocessor chips for revolutionary molecular spectroscopy simulation

Engineering researchers have successfully developed a quantum microprocessor chip for molecular spectroscopy simulation of actual large-structured and complex molecules. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Groundbreaking study shows promise for early detection and intervention in psychotic disorders such as schizophrenia

Researchers uncover a link between cognition and brain networks prior to psychotic break in individuals at risk of psychotic disorders like schizophrenia. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Adaptive 3D printing system to pick and place bugs and other organisms

A new adaptive 3D printing system can identify the positions of randomly distributed organisms and safely move them to specific locations for assembly. Read more ›

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ScienceDaily
ScienceDaily 3 place · 08/20/2024 12:44 EDT

Investigating the interplay of folding and aggregation in supramolecular polymer systems

Scientists have developed photoresponsive supramolecular polymers that can undergo both intrachain folding and interchain aggregation. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

A new reaction to enhance aromatic ketone use in chemical synthesis

Researchers develop a one pot process to transform aromatic ketones to esters, offering advancements in pharmaceutical synthesis and materials science. Read more ›

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ScienceDaily
ScienceDaily · 08/20/2024 12:44 EDT

Analyzing 'Finnegans Wake' for novel spacing between punctuation marks

James Joyce's tome 'Finnegans Wake' famously breaks the rules of normal prose through its unusual, dreamlike stream of consciousness, and new work in chaos theory takes a closer look at how Joyce's challenging novel stands out mathematically. Researchers compared the distribution of punctuation marks in various experimental novels to determine the underlying order of 'Finnegans Wake' and by statistically analyzing the texts, researchers found the tome exhibits an unusual but... Read more ›

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